Contemporary organosilicon chemistry
نویسندگان
چکیده
منابع مشابه
Contemporary organosilicon chemistry
Editorial for the Thematic Series on Contemporary Organosilicon Chemistry.
متن کاملCombinatorial chemistry and contemporary pharmacology.
Both solid- and liquid-phase combinatorial chemistry have emerged as powerful tools for identifying pharmacologically active compounds and optimizing the biological activity of a lead compound. Complementary high-throughput in vitro assays are essential for compound evaluation. Cell-based assays that use optical endpoints permit investigation of a wide variety of functional properties of these ...
متن کاملOrganosilicon therapy in Alzheimer's disease?
I was immediately intrigued by the title of the paper by Friedman and colleagues [7]. A tumult of thoughts ensued as I fought for a basis for linking organosiloxanes with the treatment of neurodegenerative disease! Needless to say, I was surprised at the authors’ contention that organosiloxanes might be used therapeutically to prevent or dissolve metal-mediated deposits of brain amyloid though ...
متن کاملPerspectives in Pharmacology Combinatorial Chemistry and Contemporary Pharmacology
Both solidand liquid-phase combinatorial chemistry have emerged as powerful tools for identifying pharmacologically active compounds and optimizing the biological activity of a lead compound. Complementary high-throughput in vitro assays are essential for compound evaluation. Cell-based assays that use optical endpoints permit investigation of a wide variety of functional properties of these co...
متن کاملSome highly sterically hindered organosilicon compounds
The chemistry of organometallic compounds with bulky ligands such as (Me3Si)3C(Tsi) or (Me2PhSI)3C(Tpsi) attached to a variety of metal centres is reviewed. The compounds Tsi2M (M = Zn, Cd, Hg) and the rare two co-ordinate TsiMn show exceptional thermal and hydrolytic stability. The corresponding alkylmetal halides form ring or cage structures. In a range of new boron compounds the structures o...
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ژورنال
عنوان ژورنال: Beilstein Journal of Organic Chemistry
سال: 2007
ISSN: 1860-5397
DOI: 10.1186/1860-5397-3-4